Programme
Day 1 (Sunday, 15th May 2016) : Joint H3Africa/AfSHG Day
| 07H30 - 08H30 | REGISTRATION |
| 8:30 | Nature Genetics Training workshop on research leadership |
| Chairs: Mboup Souleymane* (Senegal) and Raj Ramesar*(South Africa) | |
| 8:30 | A Perspective on the Context of Genetic Research in H3Africa (Barry Bloom, USA) |
| 9:00 | Managing a team and building capacity (Siana Nkya Mtatiro, Tanzania) |
| 9:30 | Communicating effectively with decision makers (Clement Adebamowo, Nigeria/USA) |
| 9:50 | Ethical leadership in research (Ruth Chadwick, UK) |
| 10:10 | Useful high impact publications (Myles Axton*, Editor of Nature Genetics) |
| 10:30 | Cofee breack |
| Session 1 | OPENING CEREMONY |
| Chairs: Rokhaya Ndiaye (Senegal) / Ambroise Wonkam (AfSHG) | |
| 11:00 | Welcome address by the President of the LOC (Rokhaya Ndiaye) |
| 11:15 | Opening remarks by H3Africa Steering Committee co-Chair (Enock Matovu) |
| 11:30 | Opening remarks by AfSHG President (Michèle Ramsay) |
| 11:45 | Allocution of the Ministry of Higher Education and Scientific Research, Senegal (SE Prof Mary Teuw Niane) |
| 12:00 | Keynote: Charles Rotimi (NIH, USA) |
| The African Society of Human Genetics: Looking back to shape the future | |
| 13H00 | LUNCH BREAK AND POSTER SESSION 1 |
| Session 2 | Panel discussion: Funding sustainable genomic research in Africa |
| Chairs: Charles Rotimi* (NIH, USA) / Audrey Duncanson* (WT, UK ) | |
| 14:00 | Position statement panellists: |
| Serigne Magueye Gueye - UCAD (Senegal), | |
| Gavin Churchyard - Aurum Institute (South Africa) | |
| Thomas Kariuki - AESA (Kenya) | |
| Rizwana Mia - MRC SHIP (South Africa) | |
| Ereck Chakauya - SANBio (South Africa) | |
| Session 3 | H3Africa SNP Array: Updates and Opportunities |
| Chair: Adebowale Adeyemo (USA) | |
| 15:30 | Nicola Mulder (South Africa) |
| 15:50 | Zané Lombard ( South Africa) |
| 16:10 | Cofee breack |
| Session 4 | Human- non-human system studies Symposium: TB genomics |
| Chair: Scott Williams (USA) / Branwen Hennig (UK) | |
| 16:40 | Invited Speaker 1: Sebastien Gagneux (Switzerland): Evolution of Mycobacterium tuberculosis |
| Invited Speaker 2: Scott Williams (USA): A TB resistance locus in highly susceptible individuals | |
| 17:30 | Special Communication : Bernie Jones (STI4D, UK): Genetics research across Africa – improving outreach and collaboration |
| 18:00 | Annual General Meeting of AfSHG |
| 19:00 | Reception cocktail |
Day 2 (Monday, 16th May 2016)
| Session 5 | Early bird session Training Workshop |
| 8:00 | Next generation sequence data analysis in complex traits: principles and examples |
| Chairs: Fasil Ayele (NIH) / Amadou Gaye (NIH) | |
| Session 6 | Cancer Genetics/Genomics with the Cancer Research Group (GERC), Senegal |
| Chairs: DEM Ahmadou (Senegal) / Raj Ramesar (South Africa) | |
| 9:00 | Guest speaker 1: Clement Adebamowo (Nigeria, US): Cervical cancer and genomics |
| 9:25 | Guest speaker 2 : Macoura Gadji (Senegal): Nuclear Remodelling and Genomic Instability in Cancer |
| 9:50 - 10:40 | Free communications |
| 9:50 – 10:00 | C01 - Utility of a microarray diagnostic for AML in the South African setting (Marco Alessandrini, South Africa |
| 10:00 – 10:10 | C02 - Aspects moléculaires des patients opérés de cancer colorectal à TOURS, (Fatou Diallo, Senegal) |
| 10:10 – 10:20 | C03 - Genetics and Pharmacogenetics Aspects of Chronic Myeloid Leukemia in Morocco (Kassogue, Morocco) |
| 12:00 – 10:30 | C04 - L’allèle arginine du codon 72 du gène p53 serait un facteur de risque de cancer du sein au Sénégal (Yacouba Dia, Senegal) |
| 13:00 – 10:40 | C05 - Place de la cytogénétique et de la biologie moléculaire dans le diagnostic et le suivi des patients atteints de leucémie myéloïde chronique (Nata Dieng, Senegal) |
| 10:40 | Cofee breack |
| Session 7 | Medical Genetic Services |
| Chairs: Pr Oumar Faye (Senegal)/ Ambroise Wonkam (South Africa) | |
| 11:00 | Guest Speaker 1: Guest Speaker 1: Lukusa-Tshilobo (RD Congo): Human and clinical genetics in the DR Congo: a rapidly evolving story |
| 11:20 | Guest Speaker 2: Leon Mutesa (Rwanda): Medical genetic services in Rwanda: achievements, challenges and perspectives |
| 11:40 | Guest speaker 3: Arame Ndiaye (Senegal): Medical genetic services in Senegal |
| 12:00 - 12:50 | Free communications |
| 12: 00 – 12:10 | C06 – Genetic counseling competencies of nurses in Three Nigerian teaching hospitals (Adejumo Prisca Olabisi, Nigeria) |
| 12: 10 – 12:20 | C07 – Caractérisation des anomalies de développement sexuel (ADS) à travers la cytogénétique: à propos de 40 cas rencontrés au Sénégal (Fatimatou Dia, Senegal) |
| 12: 20 – 12:30 | C08 – Diversité et évolution génétique des tumeurs malignes du sein chez les femmes Sénégalaises (Fatimata Mbaye, Senegal) |
| 12: 30 – 12:40 | C09 – Genetics of congenital heart disease (CHD) in Morocco: Experience of Medical Genetics and Cardio-Pediatrics departments of Fez Hassan II University Hospital (Ihssane El Bouchikhi, Morocco) |
| 13:00 | LUNCH BREAK AND POSTER SESSION 2 |
| Session 8 | Genetics of Infectious Diseases |
| Chair: Melanie Newport (UK) / Cheikh Saad Bouh Boye (Senegal) | |
| 14:00 | Guest speaker 1: Daouda Ndiaye (Senegal): Malaria genomics |
| 14:25 | Guest Speaker 2: Christian Happi (Nigeria): Genomic Surveillance Facilitates Ebola Virus Containment and Elucidates Origin, Transmission and Evolution during the 2014 Outbreak |
| 14:50 | Guest Speaker 3:Collet Dandara (South Africa): Pharmacogenomics of antiretroviral |
| 15:15 | Guest speaker 4: Dissou Affolabi (Benin): TB genomic susceptibility in Benin |
| 15:40 - 16:10 | Free communications |
| 15:40 – 15:50 | C10 – The Predictive Value of IL-28B Gene Polymorphism in Egyptian HCV Patients’ Response to Combination Therapy of Pegylated Interferon and Ribavirin (Samar Kamal Kassim, Egypt) |
| 15:50 – 16:00 | C11 – Temporal dynamics of genome-wide transcription in malarial children in Burkina Faso (Aïssatou Diawara, Emirates) |
| 16:00 – 16:10 | C12 – Real-time expression profile of Mycobacterium tuberculosis Thymidylate Kinase messenger ribo-nucleic acids during in-vitro growth of a Ugandan strain (Ivan Mwebaza, Uganda |
| 16:10 | Cofee breack |
| Session 9 | Human Genetic Diversity and Health |
| Chairs: Mbacke Sembene (Senegal) / Alice Matimba (Zimbabwe) | |
| 16:30 | Guest speaker 1: Adebowale Adeyemo (USA): Human diversity and Precision Medicine |
| 16:55 | Guest Speaker 2: Muntaser Ibrahim (Sudan): The pivotality of the north East African scenery to early human evolution |
| 17:20 | Guest speaker 3: Patrick Curmi (France |
| 17:35 | Guest speaker 4: Amadou Gaye (NIH/Senegal) Study of severe hypertension in African American |
| 18:10 - 16:30 | Free communications (3) |
| 18:00 – 18:10 | C13 – Whole Exome Sequence Analysis Identifies Two Novel Loci for High Density Lipoprotein Cholesterol in African Ancestry Individuals (Amy Bentley, USA |
| 18:10 – 18:20 | C14 – Southern African Human Genome Programme: Deep whole genome sequencing provides insights into the genetic architecture of South Africans (Ananyo Choudhury, South Africa) |
| 18:20 – 18:30 | C15 – Genomic Diversity of African populations and pharmacogenomics in the safe and efficacious use medicines in Africa (Collen Masimirembwa, Zimbabwe) |
| 20:30 | GALA DINNER |
Day 3 (Tuesday, 17th May 2016)
| Session 10 | Genomic Medicine |
| Chairs: Rokhaya Ndiaye (Senegal) / Michèle Ramsay (South Africa) | |
| 8:30 | Guest Speaker 1: Benoit Arveiler (France): New Generation Sequencing for molecular diagnosis in clinical laboratories: study of a large series of patients with albinism |
| 8:55 | Guest Speaker 2: Kenneth Fischbeck (USA)/ Guida Landouré (USA & Mali); Neurogenetic diseases study: the case of Mali |
| 9:30 | Guest Speaker 3: Henriette Poaty (Congo Brazzaville): Les gènes MisMatch Repair et le Syndrome de Lynch |
| 9:50 | Guest Speaker 4: Anatole Laleye (Benin) |
| 10:10 | Cofee breack |
| 10:30 - 11:20 | Free communications |
| 10: 30 – 10:40 | C16 – Targeted resequencing of genes involved in neurological conditions in South African patients with Parkinson’s disease (Soraya Bardien, South Africa) |
| 10: 40 – 10:50 | C17 – Knowledge and experiences of parents with children affected by Sickle Cell Disease in Cape Town (Katryn van Niekerk, South Africa) |
| 10: 50 – 11:00 | C18 – Hereditary spastic paraplegias: Identification of a novel SPG57 variant affecting TFG oligomerization and description of HSP subtypes in Sudan (Yahia Ashraf, Sudan) |
| 11: 00 – 11:10 | C19 – Genome-wide analysis identifies an African specific variant in SEMA4D that is associated with BMI (GuanJie Chen, USA |
| 11: 10 – 11:20 | C20 – Genome-wide Association Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease (David Tea Okou, USA) |
| Session 11 | Ethics and genomics |
| Chairs: Alioune Dieye (Senegal) and Jantina de Vries (South Africa) | |
| 11:20 | Guest speaker 1: Guest speaker 1: Aissatou Toure (Senegal) |
| 11:45 | Guest speaker 2: Elonna Obiefuna (Nigeria): Indigenous linguistic and cultural concepts of heritability and comprehension of genomic research in Nigeria |
| 12:10 - 12:40 | Free communications |
| 12:10 – 12:20 | C21 – Rapid Ethical Appraisal (REA) tool to design a contextualized consent process for a genetic study of podoconiosis in Ethiopia (Tewodros Tariku Gebresilase, Ethiopia). |
| 12:20 – 12:30 | C22 – Types of albinism in southern Africa and genetic investigation of pigment- related genes (Robyn Kerr, South Africa) |
| 12:30 – 12:40 | C23 – Alleviating the Burden of Beta-Thalassemia in Egypt (Ghada Yousef El-Kamah, Egypt) |
| 13:00 | LUNCH BREAK AND POSTER SESSION 3 |
| Session 12 | Disorders of Sex Development Symposium |
| 14:00 | Chairs: Oumar Faye (Senegal) / Ibrahima Fall (Senegal) |
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Invited Speaker 1: Alassane Diouf, Gynaecologist Invited Speaker 2: Haby Signate Sy, Paediatrician Invited Speaker 3: Oumar Faye, Geneticist Invited Speaker 4: Ambroise Wonkam, Geneticist Invited Speaker 5: Ibrahima Fall, Surgeon Invited Speaker 6: Aida Sylla, Psychologist |
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| 15:30 | CLOSING CEREMONY and PRIZE GIVING |
| Pr Ibrahima THIOUB, Vice Chancellor, University Cheikh Anta Diop (Senegal) | |
| Michèle Ramsay, President of the AfSHG and Chair of the H3Africa Consortium Steering Committee | |
| 16:30 – 18:30 | SOCIAL EVENT –VISIT TO GOREE ISLAND |
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